CRISPR-Cas: more than ten years and still full of mysteries

More than ten years of DOTS in Bosnia and Herzegovina.

Directly Observed Therapy Short-course (DOTS) is composed of five distinct elements: political commitment, case detection through quality-assured bacteriology; drug supplies; surveillance and monitoring systems and use of highly efficacious regimens; and direct observation of treatment. DOTS produces cure rates of up to 95 percent even in the poorest countries and prevents the development of Mu...

Handedness frequency over more than ten thousand years.

Although there are quite important geographical variations in the frequency of left-handers around the world, nothing is known about its temporal evolution. During the upper Palaeolithic (ca. 35,000-10,000 YBP), humans painted 'negative hands' by blowing pigments with a tube onto one hand applied on the rock in caves in Western Europe, by blowing pigments on their own hand through a tube held i...

[Ten years of HIV-AIDS epidemic in more than 60 years in Federal District--Brazil].

INTRODUCTION The progressive increase in number of HIV/AIDS cases in old age brings the necessity of studies about the specificities of this phenomenon by region. OBJECTIVE To identify the epidemiology in AIDS cases diagnosed in Distrito Federal - Brasil, in individuals aged > 60 years old. METHODS We conducted a time serie study with secondary data from SINAN/AIDS for the period January 19...

More than 50 years of parallel processing and still no easy path to speedup

Subaortic stenosis: still more questions than answers.